ICH Q1B Photostability tests seen in a whole new light
The 1996 guideline CPMP/ICH/279/95 Q1B describes the process for carrying out photostability tests on new active substances and medicinal products.
The pH value is a key factor in cell and tissue cultures
The term “pH” is derived from either “pondus hydrogenii” or “potentia hydrogenii”. Both are originally Latin phrases, with “pondus hydrogenii” meaning “weight of hydrogen” and...
Contamination control in a medical laboratory
In a medical laboratory, the risk of contamination in cell cultures is incalculable – no matter how meticulously work is carried out. It certainly isn’t unheard of for risks to be...
Standardized testing procedure in the environmental simulation
Electronic components, vehicle components, assemblies ... The list of products that are subjected to some of the harshest environmental conditions during their service life is...
Correctly applying hypoxia to the growth of cell cultures
When it comes to the in vitro cultivation of demanding animal cells, simulating real physiological conditions in CO2 incubators is particularly challenging for the technology...
What exactly does "Good Laboratory Practice" (GLP) involve?
"Good Laboratory Practice", or GLP for short, refers to a quality assurance system that is applied during the pre-clinical stage of research and development. Its aim is to test...
Humidity test chambers in the pharmaceutical industry
Stability testing of new active pharmaceutical ingredients and products in accordance with the ICH Q1A(R2) guideline and photostability testing to Q1B(R2) generates important data...
Five exciting applications for CO2 incubators
CO2 incubators play an important role in medical research wherever cell cultures have to be observed in as sterile and meticulous a way as possible. They keep unwanted microbes...
What do you have to consider before buying a CO2 incubator?
Which factors feed into the decision-making process when purchasing a new CO2 incubator? This article tells you about important criteria which you absolutely must bear in mind...